All-Optical Microfluidics: Leveraging Photothermal Effects to Create Reprogrammable, Non-Invasive Virtual Valves and Pumps for High-Throughput Single-Cell Analysis.
Conventional microfluidic systems, the "lab-on-a-chip" technologies that underpin much of modern biology and chemistry, rely on a hardware-based paradigm. Their channels, mixers, valves, and pumps are physically etched into materials like glass or PDMS, creating a fixed and immutable architecture. This approach, while powerful, suffers from inherent limitations: