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Ultrasound-Induced Ferroelectric Biomagnetism: Programming Cellular Ion Channels with Picotesla Magnetic Fields to Elicit Regenerative Osteogenesis in Non-Unions

Ultrasound-Induced Ferroelectric Biomagnetism: Programming Cellular Ion Channels with Picotesla Magnetic Fields to Elicit Regenerative Osteogenesis in Non-Unions

Fracture non-unions, where bone healing fails to progress without intervention, represent a significant clinical challenge, affecting up to 10% of fractures and leading to prolonged disability and economic burden. Current treatments, such as bone grafting or electrical stimulation, often fall short in efficacy or scalability. Emerging evidence suggests that biophysical
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Biogenic Cold-Weld Carbon Fixation: Lithifying Atmospheric CO₂ into Maraging-Steel-Strength Biocement via Enzymatic Metal Coordination Networks in Alkaliphilic Microbes

Biogenic Cold-Weld Carbon Fixation: Lithifying Atmospheric CO₂ into Maraging-Steel-Strength Biocement via Enzymatic Metal Coordination Networks in Alkaliphilic Microbes

Atmospheric CO₂ levels have surged beyond 420 ppm, accelerating climate change and demanding innovative carbon capture and utilization strategies. Traditional carbon sequestration methods, such as geological storage or chemical absorption, often require high energy inputs and face scalability challenges. Biogenic processes, particularly microbially induced carbonate precipitation (MICP), offer a low-energy,
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Mycoprotein Neuroplasticity: Leveraging Fungal Biosynthesis to Engineer Neuronal Damage Mitigation in Industrial Solvent-Exposed Populations

Mycoprotein Neuroplasticity: Leveraging Fungal Biosynthesis to Engineer Neuronal Damage Mitigation in Industrial Solvent-Exposed Populations

Industrial solvents, such as toluene, xylene, and trichloroethylene, are ubiquitous in manufacturing, painting, and chemical processing industries, exposing millions of workers worldwide to neurotoxic risks. Chronic exposure to these volatile organic compounds (VOCs) can lead to neuronal damage, manifesting as cognitive impairments, reduced neuroplasticity, and increased susceptibility to neurodegenerative disorders.
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Quantum Acoustic Battery: Harvesting Phononic Topological States in Doped Graphene Nanoribbons for Room-Temperature Acoustic Energy Storage and Tunable Phononic Logic

Quantum Acoustic Battery: Harvesting Phononic Topological States in Doped Graphene Nanoribbons for Room-Temperature Acoustic Energy Storage and Tunable Phononic Logic

The quest for efficient, room-temperature energy storage and logic devices has driven innovative explorations at the intersection of quantum mechanics, materials science, and acoustics. Traditional batteries rely on electrochemical processes, but emerging paradigms leverage quantum phenomena for novel storage mechanisms. One such frontier is the quantum acoustic battery, a conceptual
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Echocardiography-Guided Cryoablation: Using Real-Time Ultrasound Imaging to Control Ice Ball Formation and Minimize Collateral Tissue Damage During Cardiac Arrhythmia Treatment

Echocardiography-Guided Cryoablation: Using Real-Time Ultrasound Imaging to Control Ice Ball Formation and Minimize Collateral Tissue Damage During Cardiac Arrhythmia Treatment

Cryoballoon ablation has become a cornerstone therapy for atrial fibrillation (AF), offering a durable and efficient method for electrically isolating the pulmonary veins (PVs), the primary source of aberrant signals in many patients. The procedure's success hinges on creating transmural, lasting lesions by applying freezing temperatures to the
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Radiolytic Degradation of Pharmaceuticals in Deep Space: Developing Novel Excipients and On-Demand Synthesis Platforms to Ensure Crew Health on Long-Duration Missions

Radiolytic Degradation of Pharmaceuticals in Deep Space: Developing Novel Excipients and On-Demand Synthesis Platforms to Ensure Crew Health on Long-Duration Missions

As humanity stands on the precipice of becoming a multi-planetary species, with crewed missions to Mars and beyond transitioning from science fiction to concrete engineering roadmaps, we must confront the immense challenge of ensuring human health far from Earth. A three-year mission to Mars will be the longest and most
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All-Optical Microfluidics: Leveraging Photothermal Effects to Create Reprogrammable, Non-Invasive Virtual Valves and Pumps for High-Throughput Single-Cell Analysis.

All-Optical Microfluidics: Leveraging Photothermal Effects to Create Reprogrammable, Non-Invasive Virtual Valves and Pumps for High-Throughput Single-Cell Analysis.

Conventional microfluidic systems, the "lab-on-a-chip" technologies that underpin much of modern biology and chemistry, rely on a hardware-based paradigm. Their channels, mixers, valves, and pumps are physically etched into materials like glass or PDMS, creating a fixed and immutable architecture. This approach, while powerful, suffers from inherent limitations: